Effects of Troglitazone on HepG2 Viability and Mitochondrial Function
نویسندگان
چکیده
منابع مشابه
Effects of troglitazone on HepG2 viability and mitochondrial function.
Troglitazone (TRO), a member of the thiazolidinedione class of drugs, has been associated with hepatotoxicity in patients. The following in vitro study was conducted to investigate the effects of TRO on mitochondrial function and viability in a human hepatoma cell line, HepG2. TRO induced a concentration- and time-dependent increase in cell death, as measured by lactate dehydrogenase release. E...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2002
ISSN: 1096-0929
DOI: 10.1093/toxsci/69.1.131